Human Serglycin/SRGN Recombinant Protein (RPES4413)

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SKU:
RPES4413
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Serglycin/SRGN Recombinant Protein

SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

Product Name:Human Serglycin/SRGN Recombinant Protein (RPES4413)
Product Code:RPES4413
Size:50µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:PPG,PRG,PRG1
Accession:CAA34900.1
Sequence:Met 1-Leu158
Fusion tag:C-His & Myc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human SRGN (Met1-Leu158) was fused with the C-terminal polyhistidine-tagged myc at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:17.3 kDa
AP Mol Mass:27 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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