Signal Transduction Recombinant Proteins

Human SENP7 Recombinant Protein (RPES4425)

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SKU:
RPES4425
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

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Human SENP7 Recombinant Protein

Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.

Product Name:Human SENP7 Recombinant Protein (RPES4425)
Product Code:RPES4425
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2
Accession:Q9BQF6
Sequence:Met695-Ala864
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:27.3 kDa
AP Mol Mass:25 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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