Human Semaphorin-4D/CD100 Recombinant Protein (His tag)

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SKU:
RPES5984

Description

Product Name:Human Semaphorin-4D/CD100 Recombinant Protein (His tag)
Product Code:RPES5984
Size:20µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:A8, SEMA4D, BB18, COLL4, Collapsin 4, GR3, MSEMA, Sema H, SEMA J, Semacl2, SemaH, Semcl 2
Mol Mass:80.63 kDa
AP Mol Mass:90 kDa
Tag:C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met1-Arg734
Accession:Q92854
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
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