Human Semaphorin-4D/CD100 Recombinant Protein (His tag)
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- SKU:
- RPES5984
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
| Product Name: | Human Semaphorin-4D/CD100 Recombinant Protein (His tag) |
| Product Code: | RPES5984 |
| Size: | 20µg |
| Species: | Human |
| Expression Host: | HEK293 Cells |
| Synonyms: | A8, SEMA4D, BB18, COLL4, Collapsin 4, GR3, MSEMA, Sema H, SEMA J, Semacl2, SemaH, Semcl 2 |
| Mol Mass: | 80.63 kDa |
| AP Mol Mass: | 90 kDa |
| Tag: | C-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Testing in progress |
| Sequence: | Met1-Arg734 |
| Accession: | Q92854 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. |
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