Human SEMA4B Recombinant Protein (RPES4281)
- SKU:
- RPES4281
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human SEMA4B Recombinant Protein
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
| Product Name: | Human SEMA4B Recombinant Protein (RPES4281) |
| Product Code: | RPES4281 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Semaphorin-4B, KIAA1745, SEMAC, SEMA4B |
| Accession: | Q9NPR2 |
| Sequence: | Leu39-Glu712 |
| Fusion tag: | C-Fc-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Semaphorin 4B is produced by our Mammalian expression system and the target gene encoding Leu39-Glu712 is expressed with a Fc; 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 102.0 kDa |
| AP Mol Mass: | 114 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 . |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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