Human Securin-2 ELISA Kit

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SKU:
HUFI00710
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9NZH5
Sensitivity:
3.75pg/ml
Range:
6.25-400pg/ml
ELISA Type:
Sandwich
Synonyms:
PTTG2, Securin-2, Pituitary tumor-transforming gene 2 protein
Reactivity:
Human

Description

Human Securin-2 ELISA

Securin-2 is a 22 kDa protein that is crucial for the stability of the cells' genome. Securin-2 regulates cell cycle progression by preventing premature sister-chromatid separation during mitosis. Securin-2 deficiency leads to autosomal recessive mental retardation with specific dysmorphism (AR-MR-D), a syndrome which is characterized by mental retardation, frequent epileptic seizures and dysmorphic features of the face. Securin-2 is also associated with neurodegenerative disorders such as alzheimer's disease and schizophrenia.

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