Human Secretogranin 3/SCG3 Recombinant Protein (RPES3334)

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SKU:
RPES3334
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Secretogranin 3/SCG3 Recombinant Protein

SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.

Product Name:Human Secretogranin 3/SCG3 Recombinant Protein (RPES3334)
Product Code:RPES3334
Size:50µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:Secretogranin-3,Secretogranin III,SgIII,
Accession:AAH14539.1
Sequence:Met 1-Leu468
Fusion tag:C-His
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human SCG3 (AAH14539.1) (Met1-Leu468) was expressed with a C-terminal polyhistidine tag.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:52.4 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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