Human SDF2 Recombinant Protein (RPES4878)
- SKU:
- RPES4878
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human SDF2 Recombinant Protein
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.
| Product Name: | Human SDF2 Recombinant Protein (RPES4878) |
| Product Code: | RPES4878 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | SDF2 |
| Accession: | NP_008854.2 |
| Sequence: | Met 1-Leu 211 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the pro form of human SDF2 (NP_008854.2) (Met 1-Leu 211) was expressed with a C-terminal polyhistidine tag. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 22.7 kDa |
| AP Mol Mass: | 22.7 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 0.5mM PMSF, 0.5mM EDTA, 0.5mM TCEP, 10% glycerol |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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