Human SCRN1 Recombinant Protein (RPPB4599)

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SKU:
RPPB4599
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q12765

Description

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Product Name:Human SCRN1 Recombinant Protein
Product Code:RPPB4599
Size:20µg
Species:Human
Target:SCRN1
Synonyms:Secernin-1, SES1, KIAA0193, Secernin 1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:SCRN1 protein solution (0.5mg/ml) containing Phosphatebuffered saline (pH7.4) , 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:GSSHHHHHH SSGLVPRGSH MGSMAAAPPS YCFVAFPPRA KDGLVVFGKN SARPRDEVQE VVYFSAADHEPESKVECTYI SIDQVPRTYA IMISRPAWLW GAEMGANEHG VCIANEAINT REPAAEIEAL LGMDLVRLGLERGETAKEAL DVIVSLLEEH GQGGNYFEDA NSCHSFQSAY LIVDRDEAWV LETIGKYWAA EKVTEGVRCICSQLSLTTKM DAEHPELRSY AQSQGWWTGE GEFNFSEVFS PVEDHLDCGA GKDSLEKQEE SITVQTMMNTLRDKASGVCI DSEFFLTTAS GVSVLPQNRS SPCIHYFTGT PDPSRSIFKP FIFVDDVKLV PKTQSPCFGDDDPAKKEPRF QEKPDRRHEL YKAHEWARAI IESDQEQGRK LRSTMLELEK QGLEAMEEIL TSSEPLDPAE VGDLFYDCVDTEIKFFK
UniProt Code:Q12765

Secernin 1 (SCRN1) which is a member of the peptidase C69 family, regulates exocytosis in mast cells. SCRN1 increases both the level of secretion and the sensitivity of mast cells to stimulation with calcium.

SCRN1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 437 amino acids (1-414 a.a) andhaving a molecular mass of 48.8kDa.SCRN1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

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