Human SCAND1 Recombinant Protein (RPPB4587)
- SKU:
- RPPB4587
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P57086
Description
| Product Name: | Human SCAND1 Recombinant Protein |
| Product Code: | RPPB4587 |
| Size: | 10µg |
| Species: | Human |
| Target: | SCAND1 |
| Synonyms: | RAZ1, SDP1, SCAN domain containing 1, SCAN-related protein RAZ1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The SCAND1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0) 1mM DTT, 100mM NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM LVQEQLLAIL PEAARARRIR RRTDVRITG |
SCAND1 is a part of a family of genes which encode an isolated SCAN domain. SCAN domain containing 1 has one SCAN box domain and has no zinc finger motif, which distinct this protein from almost all other SCAN domain containing proteins. SCAND1 is a nuclear protein that takes a part in the mechanism of transcription regulation. SCAND1 is extensively expressed in high levels in the kidney, thyroid, liver, prostate and testis.
SCAND1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (1-179 a.a.) and having a molecular mass of 21.2kDa (molecular weight on SDS-PAGE will appear higher).SCAND1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SCAND1: may regulate transcriptional activity. Contains a SCAN domain, which mediates protein interactions. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 20q11.1-q11.23 Cellular Component: nucleus Molecular Function:identical protein binding; protein binding; transcription factor activity |
| NCBI Summary: | This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011] |
| UniProt Code: | P57086 |
| NCBI GenInfo Identifier: | 10720272 |
| NCBI Gene ID: | 51282 |
| NCBI Accession: | P57086.1 |
| UniProt Secondary Accession: | P57086,Q6IAG7, |
| UniProt Related Accession: | P57086 |
| Molecular Weight: | 19,082 Da |
| NCBI Full Name: | SCAN domain-containing protein 1 |
| NCBI Synonym Full Names: | SCAN domain containing 1 |
| NCBI Official Symbol: | SCAND1�� |
| NCBI Official Synonym Symbols: | RAZ1; SDP1�� |
| NCBI Protein Information: | SCAN domain-containing protein 1 |
| UniProt Protein Name: | SCAN domain-containing protein 1 |
| Protein Family: | SCAN domain-containing protein |
| UniProt Gene Name: | SCAND1�� |
| UniProt Entry Name: | SCND1_HUMAN |
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