Human SAE1 ELISA Kit

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SKU:
HUFI01924
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9UBE0
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
SAE1, AOS1, SUA1, UBA2, UBLE1A, AOS1activator of SUMO1, FLJ3091, HSPC140, Sua1, SUA1sentrin, SUMO-activating protein AOS1, SUMO-1 activating enzyme E1 N subunit, SUMO1 activating enzyme subunit 1, SUMO-1 activating enzyme subunit 1, SUMO-activating e
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human SAE1 ELISA

The SUE1 (SUMO1 Activating Enzyme Subunit 1) protein functions as a heterodimer with UBA2 and acts as a sumoylating enzyme by combining to form the SUMO-activating complex. After translocation, protein sumoylation, also known as SUMO modification, controls protein structure and intracellular localisation. Ogden syndrome and adult dermatomyositis are two examples of diseases linked to SAE1. The protein metabolism pathway, as well as the proteolysis putative SUMO-1 pathway, are among the pathways it is involved in.

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