Cytokines Recombinant Proteins
Human SAA4 Recombinant Protein (RPPB0945)
- SKU:
- RPPB0945
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P35542
- Research Area:
- Cytokines
Description
| Product Name: | Human SAA4 Recombinant Protein |
| Product Code: | RPPB0945 |
| Size: | 10µg |
| Species: | Human |
| Target: | SAA4 |
| Synonyms: | Serum amyloid A-4 protein, Constitutively expressed serum amyloid A protein, C-SAA, SAA4, CSAA. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SAA4 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 5mM DTT, 0.2M NaCl and 0.5mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MWRSFFKEAL QGVGDMGRAY WDIMISNHQN SNRYLYARGN YDAAQRGPGG VWAAKLISRS RVYLQGLIDY YLFGNSSTVL EDSKSNEKAE EWGRSGKDPD RFRPDGLPKK Y |
SAA4 is a constitutively expressed protein which is a member of the SAA family. SAA4 is a major acute phase reactant and an apolipoprotein of the HDL complex. SAA4 is constitutively expressed only in humans and mice; it is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown, and its serum concentration has no association with those of other major apolipoproteins. SAA4 mRNA and protein occurrence in macrophage derived foam cells of coronary and carotid arteries implied a specific role of human SAA4 during inflammation including atherosclerosis.
SAA4 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 131 amino acids (21-130 a.a.) and having a molecular mass of 14.9kDa. The SAA4 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SAA4: Major acute phase reactant. Apolipoprotein of the HDL complex. Belongs to the SAA family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11p15.1-p14 Cellular Component: extracellular space Molecular Function:chemoattractant activity |
| UniProt Code: | P35542 |
| NCBI GenInfo Identifier: | 296452894 |
| NCBI Gene ID: | 6291 |
| NCBI Accession: | P35542.2 |
| UniProt Secondary Accession: | P35542,Q6FHJ4, |
| UniProt Related Accession: | P35542 |
| Molecular Weight: | 14,747 Da |
| NCBI Full Name: | Serum amyloid A-4 protein |
| NCBI Synonym Full Names: | serum amyloid A4, constitutive |
| NCBI Official Symbol: | SAA4�� |
| NCBI Official Synonym Symbols: | CSAA; C-SAA�� |
| NCBI Protein Information: | serum amyloid A-4 protein |
| UniProt Protein Name: | Serum amyloid A-4 protein |
| UniProt Synonym Protein Names: | Constitutively expressed serum amyloid A protein; C-SAA |
| Protein Family: | Serum amyloid A-4 protein |
| UniProt Gene Name: | SAA4�� |
| UniProt Entry Name: | SAA4_HUMAN |
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