Human S100A10 Recombinant Protein (RPPB4546)
- SKU:
- RPPB4546
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P60903
Description
| Product Name: | Human S100A10 Recombinant Protein |
| Product Code: | RPPB4546 |
| Size: | 10µg |
| Species: | Human |
| Target: | S100A10 |
| Synonyms: | Protein S100-A10, S100 calcium-binding protein A10, Calpactin-1 light chain, Calpactin I light chain, p10 protein, p11, Cellular ligand of annexin II, S100A10, ANX2LG, CAL1L, CLP11, 42C, p10, GP11, ANX2L, Ca[1], MGC111133. |
| Source: | Escherichia Coli |
| Formulation: | S100-A10 is supplied in 1xPBS and 50% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 1-2 weeks.�Store, frozen at -20°C for longer periods of time.�Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE.2 bands on Western blot at 15.3 and 30.6 kDa, respectively representing monomeric and dimeric form. |
S100A10 is a member of the S100 family of proteins contains two EF-hand calcium-binding motifs and is thought to be involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. S100A10 may function in exocytosis and endocytosis.
S100A10 Human Recombinant also called Calpactin light chain is expressed in E. coli having a molecular weight of 15.3kDa fused to an amino terminal hexahistidine tag.
| UniProt Protein Function: | S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family. |
| UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 1q21 Cellular Component: extrinsic to plasma membrane; lipid raft Molecular Function:protein binding; protein homodimerization activity; calcium ion binding; lipid binding Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P60903 |
| NCBI GenInfo Identifier: | 46397706 |
| NCBI Gene ID: | 6281 |
| NCBI Accession: | P60903.2 |
| UniProt Related Accession: | P60903 |
| Molecular Weight: | 11kDa |
| NCBI Full Name: | Protein S100-A10 |
| NCBI Synonym Full Names: | S100 calcium binding protein A10 |
| NCBI Official Symbol: | S100A10�� |
| NCBI Official Synonym Symbols: | 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG�� |
| NCBI Protein Information: | protein S100-A10 |
| UniProt Protein Name: | Protein S100-A10 |
| UniProt Synonym Protein Names: | Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A10�� |
| UniProt Entry Name: | S10AA_HUMAN |
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