Human RWDD1 Recombinant Protein (RPPB4540)

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RPPB4540

Description

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Product Name:Human RWDD1 Recombinant Protein
Product Code:RPPB4540
Size:10µg
Species:Human
Target:RWDD1
Synonyms:RWD domain-containing protein 1, DRG family-regulatory protein 2, RWDD1, DFRP2, CGI-24, PTD013.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RWDD1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 2mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMTDYGEE QRNELEALES IYPDSFTVLS ENPPSFTITV TSEAGENDET VQTTLKFTYS EKYPDEAPLY EIFSQENLED NDVSDILKLL ALQAEENLGM VMIFTLVTAV QEKLNEIVDQ IKTRREEEKK QKEKEAEEAE KQLFHGTPVT IENFLNWKAK FDAELLEIKK KRMKEEEQAG KNKLSGKQLF ETDHNLDTSD IQFLEDAGNN VEVDESLFQE MDDLELEDDE DDPDYNPADP ESDSAD

RWD Domain Containing 1 (RWDD1) is a member of the RWDD1/GIR2 family. The RWDD1 protein protects DRG2 (developmentally regulated GTP binding protein 2), from proteolytic degradation. RWD domain refers to 3 signature motifs in proteins: RING finger, WD-repeats, and yeast DEAD (DEXD)-like motif. Current evidence proposes that RWD domain may be required for protein-protein interaction.

RWDD1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 266 amino acids (1-243 a.a.) and having a molecular mass of 30.3kDa (Molecular size on SDS-PAGE will appear higher).RWDD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:RWDD1: Protects DRG2 from proteolytic degradation. Belongs to the RWDD1/GIR2 family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 6q13-q22.33

Molecular Function:protein binding

UniProt Code:Q9H446
NCBI GenInfo Identifier:34098713
NCBI Gene ID:51389
NCBI Accession:Q9H446.1
UniProt Secondary Accession:Q9H446,Q9Y313, Q9Y6B3, A8K3W2, A8MT24,
UniProt Related Accession:Q9H446
Molecular Weight:17,082 Da
NCBI Full Name:RWD domain-containing protein 1
NCBI Synonym Full Names:RWD domain containing 1
NCBI Official Symbol:RWDD1��
NCBI Official Synonym Symbols:CGI-24; PTD013��
NCBI Protein Information:RWD domain-containing protein 1
UniProt Protein Name:RWD domain-containing protein 1
UniProt Synonym Protein Names:DRG family-regulatory protein 2
Protein Family:RWD domain-containing protein
UniProt Gene Name:RWDD1��
UniProt Entry Name:RWDD1_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9H446
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