Human RWDD1 Recombinant Protein (RPPB4540)
- SKU:
- RPPB4540
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H446
Description
| Product Name: | Human RWDD1 Recombinant Protein |
| Product Code: | RPPB4540 |
| Size: | 10µg |
| Species: | Human |
| Target: | RWDD1 |
| Synonyms: | RWD domain-containing protein 1, DRG family-regulatory protein 2, RWDD1, DFRP2, CGI-24, PTD013. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RWDD1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMTDYGEE QRNELEALES IYPDSFTVLS ENPPSFTITV TSEAGENDET VQTTLKFTYS EKYPDEAPLY EIFSQENLED NDVSDILKLL ALQAEENLGM VMIFTLVTAV QEKLNEIVDQ IKTRREEEKK QKEKEAEEAE KQLFHGTPVT IENFLNWKAK FDAELLEIKK KRMKEEEQAG KNKLSGKQLF ETDHNLDTSD IQFLEDAGNN VEVDESLFQE MDDLELEDDE DDPDYNPADP ESDSAD |
RWD Domain Containing 1 (RWDD1) is a member of the RWDD1/GIR2 family. The RWDD1 protein protects DRG2 (developmentally regulated GTP binding protein 2), from proteolytic degradation. RWD domain refers to 3 signature motifs in proteins: RING finger, WD-repeats, and yeast DEAD (DEXD)-like motif. Current evidence proposes that RWD domain may be required for protein-protein interaction.
RWDD1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 266 amino acids (1-243 a.a.) and having a molecular mass of 30.3kDa (Molecular size on SDS-PAGE will appear higher).RWDD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RWDD1: Protects DRG2 from proteolytic degradation. Belongs to the RWDD1/GIR2 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6q13-q22.33 Molecular Function:protein binding |
| UniProt Code: | Q9H446 |
| NCBI GenInfo Identifier: | 34098713 |
| NCBI Gene ID: | 51389 |
| NCBI Accession: | Q9H446.1 |
| UniProt Secondary Accession: | Q9H446,Q9Y313, Q9Y6B3, A8K3W2, A8MT24, |
| UniProt Related Accession: | Q9H446 |
| Molecular Weight: | 17,082 Da |
| NCBI Full Name: | RWD domain-containing protein 1 |
| NCBI Synonym Full Names: | RWD domain containing 1 |
| NCBI Official Symbol: | RWDD1�� |
| NCBI Official Synonym Symbols: | CGI-24; PTD013�� |
| NCBI Protein Information: | RWD domain-containing protein 1 |
| UniProt Protein Name: | RWD domain-containing protein 1 |
| UniProt Synonym Protein Names: | DRG family-regulatory protein 2 |
| Protein Family: | RWD domain-containing protein |
| UniProt Gene Name: | RWDD1�� |
| UniProt Entry Name: | RWDD1_HUMAN |
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