Human RUNX2 / CBFA1 ELISA Kit

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SKU:
HUFI02074
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q13950
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
RUNX2, CBFA1, Acute myeloid leukemia 3 protein, AML3CCD, Core-binding factor subunit alpha-1, PEA2-alpha A, PEBP2A, PEBP2A1CCD1, PEBP2aA1, PEBP2-alpha A, runt domain, alpha subunit 1, runt-related transcription factor 2, SL3, AKV core-binding factor
Reactivity:
Human
Research Area:
Developmental Biology

Description

Human RUNX2 / CBFA1 ELISA

RUNX2 / CBFA1 encodes a nuclear protein which is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. Mutations in the RUNX2 / CBFA1 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD), maxillary hypoplasia and brachydactyly. The Assay Genie Human RUNX2/CBFA1 ELISA is a highly sensitive assay for the quantitative measurement of RUNX2/CBFA1 in serum, blood, plasma, cell culture supernatant and tissue samples.

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