Human RRM2 / Ribonucleoside-diphosphate reductase subunit M2 B ELISA Kit

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SKU:
HUFI01125
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P31350
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
RRM2, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human RRM2 / Ribonucleoside-diphosphate reductase subunit M2 B ELISA Kit

RRM2 is one of two non-identical ribonucleotide reductase subunits. The formation of deoxyribonucleotides from ribonucleotides is catalysed by this reductase. The encoded protein (M2) is synthesised in a cell-cycle-dependent manner. RRM2 transcription can start from two different promoters, resulting in two isoforms with different N-termini lengths. On chromosomes 1 and X, related pseudogenes have been discovered. Diamond-Blackfan Anemia 20 and Choriocarcinoma are two diseases linked to RRM2. E2F-mediated DNA replication regulation and Pyrimidine metabolism are two related pathways to RRM2.

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