Human RPS5 Recombinant Protein (RPPB4510)

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RPPB4510

Description

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Product Name:Human RPS5 Recombinant Protein
Product Code:RPPB4510
Size:10µg
Species:Human
Target:RPS5
Synonyms:40S ribosomal protein S5, S5, RPS5.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:RPS5 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMTEWETA APAVAETPDI KLFGKWSTDD VQINDISLQD YIAVKEKYAK YLPHSAGRYA AKRFRKAQCP IVERLTNSMM MHGRNNGKKL MTVRIVKHAF EIIHLLTGEN PLQVLVNAII NSGPREDSTR IGRAGTVRRQ AVDVSPLRRV NQAIWLLCTG AREAAFRNIK TIAECLADEL INAAKGSSNS YAIKKKDELE RVAKSNR

40S ribosomal protein S5 (RPS5) is a ribosomal protein, which is a member of the ribosomal protein S7P family.Ribosomes, which are the organelles that catalyze protein synthesis, composed of a small subunit and a large subunit that comprise of over 80 distinct ribosomal proteins. RPS5 is a 204 amino acid component of the 40S complex. RPS5 proteins exist as multiple processed pseudogenes which are scattered throughout the genome. RPS5 is expressed at varying amounts in colorectal cancer cells, proposing a possible role in carconigenesis.

RPS5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a.) and having a molecular mass of 25.3kDa.RPS5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:RPS5: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:RNA-binding; Ribosomal; Translation

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: focal adhesion; membrane; ribonucleoprotein complex; cytosol

Molecular Function:mRNA binding; structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; translation; viral reproduction; regulation of translational fidelity; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; viral infectious cycle; translational termination

NCBI Summary:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P46782
NCBI GenInfo Identifier:22002064
NCBI Gene ID:6193
NCBI Accession:P46782.4
UniProt Secondary Accession:P46782,Q96BN0, B2R4T2,
UniProt Related Accession:P46782
Molecular Weight:204
NCBI Full Name:40S ribosomal protein S5
NCBI Synonym Full Names:ribosomal protein S5
NCBI Official Symbol:RPS5��
NCBI Official Synonym Symbols:S5��
NCBI Protein Information:40S ribosomal protein S5
UniProt Protein Name:40S ribosomal protein S5
Protein Family:30S ribosomal protein
UniProt Gene Name:RPS5��
UniProt Entry Name:RS5_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P46782
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