Human RPS27A Recombinant Protein (RPPB5063)

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SKU:
RPPB5063
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P62988

Description

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Product Name:Human RPS27A Recombinant Protein
Product Code:RPPB5063
Size:50µg
Species:Human
Target:RPS27A
Synonyms:Ubiquitin, Ribosomal Protein S27a, CEP80, UBA80, UBCEP1, UBCEP80, HUBCEP80, RPS27A.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered solution.
Formulation:1mg/ml containing 50mM HEPES (pH7.5) 150mM NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as estimated by SDS-PAGE.
Amino Acid Sequence:MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG

RPS27A is a small protein composed of 76 amino acids. RPS27A is found only in eukaryotic organisms among which shows strong sequence conservation. The RPS27A protein is present in all cell types, thus giving rise to its name.RPS27A is found either in free form or conjugated to proteins through a covalent bond between the glycine at the C-terminal end and the side chains of lysine.The connection of multiple copies of RPS27A targets the proteins for degradation by the 26S proteosome. RPS27A ligation is an ATP-dependent multi-step process. RPS27A is activated by the E1 enzyme. The attachment of RPS27A to the target protein is catalyzed by the E2 enzyme acting in concert with E3 which is involved in the recognition of the substrate protein.

Ubiquitin Human Recombinant expressed in E.coli and purified by ion-exchange chromatography, contains 76 amino acids and has an Mw of 8.6kDa.

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P62988
NCBI GenInfo Identifier:51703339
NCBI Gene ID:7311
NCBI Accession:P62988.1
UniProt Secondary Accession:P62988
UniProt Related Accession:P62988,P62987
Molecular Weight:
NCBI Full Name:
NCBI Synonym Full Names:ubiquitin A-52 residue ribosomal protein fusion product 1
NCBI Official Symbol:UBA52��
NCBI Official Synonym Symbols:L40; CEP52; RPL40; HUBCEP52��
NCBI Protein Information:ubiquitin-60S ribosomal protein L40
UniProt Protein Name:
UniProt Synonym Protein Names:
Protein Family:Ubiquitin
UniProt Gene Name:
UniProt Entry Name:
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