40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that belongs to the ribosomal protein S19e family. RPS19 is found in the nucleoli, and it has higher-level expression in colon carcinoma tissue than normal colon tissue. RPS19 is necessary for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 is required for a slew of biological activities, including endocrine pancreas development, erythrocyte differentiation, mRNA synthesis. RPS19 abnormalities are the reason for Diamond-Blackfan anaemia type 1 (DBA1), a form of Diamond-Blackfan anaemia, a congenital non-regenerative hypoplastic anaemia that generally manifests in early infancy. Diamond-blackfan anaemia causes moderate to severe macrocytic anaemia, erythroblastopenia, and increased cancer risk. Human RPS19 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human RPS19 Recombinant Protein (RPES1639)
Product Code:
RPES1639
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
40S Ribosomal Protein S19, RPS19
Accession:
P39019
Sequence:
Pro2-His145
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human 40S Ribosomal Protein S19 is produced by our E.coli expression system and the target gene encoding Pro2-His145 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
16.1 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Human RPS19 (Ribosomal protein S19) ELISARibosomes, the cellular organelles responsible for protein synthesis, are made up of two subunits: a small 40S and a big 60S. The 40S and 60s subunits...