Human RPS14 Recombinant Protein (RPPB4516)
- SKU:
- RPPB4516
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P62263
Description
| Product Name: | Human RPS14 Recombinant Protein |
| Product Code: | RPPB4516 |
| Size: | 5µg |
| Species: | Human |
| Target: | RPS14 |
| Synonyms: | 40S ribosomal protein S14, RPS14, S14, EMTB. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RPS14 solution (0.25 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 40% glycerol and 100mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAPRKGK EKKEEQVISL GPQVAEGENV FGVCHIFASF NDTFVHVTDL SGKETICRVT GGMKVKADRD ESSPYAAMLA AQDVAQRCKE LGITALHIKL RATGGNRTKT PGPGAQSALR ALARSGMKIG RIEDVTPIPS DSTRRKGGRR GRRL� |
Ribosomal protein S14 (RPS14) is a ribosomal protein, which is a member of the S11P family of ribosomal proteins. Ribosomes are the organelles which catalyze protein synthesis and composed of a small and a large subunit that consist of over 80 different ribosomal proteins. RPS14 is a component of the 40S subunit which localizes to the cytoplasm.
RPS14 Human Recombinant fused with a�23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�174 amino acids (1-151 a.a.) and having a molecular mass of 18.7kDa. The RPS14 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPS14: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:RNA-binding; Ribosomal; Translation Chromosomal Location of Human Ortholog: 5q31-q33 Cellular Component: focal adhesion; membrane; mitochondrion; cytoplasm; nucleolus; cytosol Molecular Function:structural constituent of ribosome; RNA binding; translation regulator activity; mRNA 5'-UTR binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; viral reproduction; translation; viral infectious cycle; negative regulation of transcription from RNA polymerase II promoter; translational termination; maturation of SSU-rRNA; regulation of translation; cellular protein metabolic process; translational elongation; translational initiation; mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; erythrocyte differentiation; gene expression; viral transcription Disease: Chromosome 5q Deletion Syndrome |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P62263 |
| NCBI GenInfo Identifier: | 50403752 |
| NCBI Gene ID: | 6208 |
| NCBI Accession: | P62263.3 |
| UniProt Secondary Accession: | P62263,P06366, Q5BJI0, B2R5G5, D3DQG5, |
| UniProt Related Accession: | P62263 |
| Molecular Weight: | 151 |
| NCBI Full Name: | 40S ribosomal protein S14 |
| NCBI Synonym Full Names: | ribosomal protein S14 |
| NCBI Official Symbol: | RPS14�� |
| NCBI Official Synonym Symbols: | S14; EMTB�� |
| NCBI Protein Information: | 40S ribosomal protein S14; emetine resistance |
| UniProt Protein Name: | 40S ribosomal protein S14 |
| Protein Family: | Ribosomal protein |
| UniProt Gene Name: | RPS14�� |
| UniProt Entry Name: | RS14_HUMAN |
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