Enzymes Recombinant Proteins

Human RPP30 Recombinant Protein (RPPB2259)

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SKU:
RPPB2259
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P78346
Research Area:
Enzymes

Description

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Product Name:Human RPP30 Recombinant Protein
Product Code:RPPB2259
Size:20µg
Species:Human
Target:RPP30
Synonyms:Ribonuclease P protein subunit p30, RNaseP protein p30, RNase P subunit 2, RPP30, RNASEP2, TSG15, FLJ38491, RP11-320F15.1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The RPP30 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 5mM DTT, 200mM NaCl and 1mM EDTA.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAVFADL DLRAGSDLKA LRGLVETAAH LGYSVVAINH IVDFKEKKQE IEKPVAVSEL FTTLPIVQGK SRPIKILTRL TIIVSDPSHC NVLRATSSRA RLYDVVAVFP KTEKLFHIAC THLDVDLVCI TVTEKLPFYF KRPPINVAID RGLAFELVYS PAIKDSTMRR YTISSALNLM QICKGKNVII SSAAERPLEI RGPYDVANLG LLFGLSESDA KAAVSTNCRA ALLHGETRKT AFGIISTVKK PRPSEGDEDC LPASKKAKCE G

Ribonuclease P protein subunit p30 (RPP30) is a member of the eukaryotic/archaeal RNase P protein component 3 family. RPP30 is component of ribonuclease P, which is a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Ribonuclease P (RNase P) is small nuclear ribonucleoprotein (snRNPs) which acts on RNA substrates in vitro. In addition, RNase P which accumulate in the nucleolus, have a similar RNA component and several protein subunits in common.

RPP30 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 291 amino acids (1-268 a.a.) and having a molecular mass of 31.8kDa. The RPP30 is purified by proprietary chromatographic techniques.

UniProt Protein Function:RPP30: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
UniProt Protein Details:

Protein type:EC 3.1.26.5; Nucleolus; Ribonuclease

Chromosomal Location of Human Ortholog: 10q23.31

Cellular Component: nucleolar ribonuclease P complex; nucleoplasm; nucleus

Molecular Function:protein binding; ribonuclease P activity; RNA binding

Biological Process: rRNA processing; tRNA 5'-leader removal; tRNA processing

UniProt Code:P78346
NCBI GenInfo Identifier:13124514
NCBI Gene ID:10556
NCBI Accession:P78346.1
UniProt Secondary Accession:P78346,B2R799, E9PB02,
UniProt Related Accession:P78346
Molecular Weight:29kDa
NCBI Full Name:Ribonuclease P protein subunit p30
NCBI Synonym Full Names:ribonuclease P/MRP subunit p30
NCBI Official Symbol:RPP30��
NCBI Official Synonym Symbols:TSG15��
NCBI Protein Information:ribonuclease P protein subunit p30
UniProt Protein Name:Ribonuclease P protein subunit p30
UniProt Synonym Protein Names:RNase P subunit 2
Protein Family:Ribonuclease P protein
UniProt Gene Name:RPP30��
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