Human RPL23A Recombinant Protein (RPPB4494)
- SKU:
- RPPB4494
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P62750
Description
| Product Name: | Human RPL23A Recombinant Protein |
| Product Code: | RPPB4494 |
| Size: | 10µg |
| Species: | Human |
| Target: | RPL23A |
| Synonyms: | L23A, MDA20, 60S ribosomal protein L23a, RPL23A, MelanomaDifferentiation-Associated Gene 20. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | RPL23A protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT and 250mM imidazole. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAPKAKK EAPAPPKAEA KAKALKAKKA VLKGVHSHKK KKIRTSPTFRRPKTLRLRRQ PKYPRKSAPR RNKLDHYAII KFPLTTESAM KKIEDNNTLV FIVDVKANKH QIKQAVKKLYDIDVAKVNTL IRPDGEKKAY VRLAPDYDAL DVANKIGII |
RPL23A is a ribosomal protein which is a component of the 60S subunit. Ribosomes, the organelles which catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally different proteins. RPL23A is a member of the L23P family of ribosomal proteins. It is located in the cytoplasm. Recombinant Human Ribosomal Protein L23A may be one of the target molecules involved in mediating growth inhibition. The corresponding protein binds to a specific site on the 26S rRNA in yeast.
RPL23A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (1-156 a.a) and having a molecular mass of 20.1kDa.RPL23A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPL23A: This protein binds to a specific region on the 26S rRNA. Belongs to the ribosomal protein L23P family. |
| UniProt Protein Details: | Protein type:Ribosomal; Translation Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: cytoplasm; nucleolus; TORC2 complex; nucleus; cytosol Molecular Function:rRNA binding; protein binding; structural constituent of ribosome; nucleotide binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; cell proliferation; cellular protein metabolic process; translational elongation; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; viral transcription; gene expression; viral infectious cycle; translational termination |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P62750 |
| NCBI GenInfo Identifier: | 51338637 |
| NCBI Gene ID: | 6147 |
| NCBI Accession: | P62750.1 |
| UniProt Secondary Accession: | P62750,P29316, P39024, Q92774, B2R5B2, |
| UniProt Related Accession: | P62750 |
| Molecular Weight: | 156 |
| NCBI Full Name: | 60S ribosomal protein L23a |
| NCBI Synonym Full Names: | ribosomal protein L23a |
| NCBI Official Symbol: | RPL23A�� |
| NCBI Official Synonym Symbols: | L23A; MDA20�� |
| NCBI Protein Information: | 60S ribosomal protein L23a; melanoma differentiation-associated gene 20 |
| UniProt Protein Name: | 60S ribosomal protein L23a |
| Protein Family: | 60S ribosomal protein |
| UniProt Gene Name: | RPL23A�� |
| UniProt Entry Name: | RL23A_HUMAN |
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