Human RPL12 Recombinant Protein (RPPB2257)

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SKU:
RPPB2257
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P30050

Description

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Product Name:Human RPL12 Recombinant Protein
Product Code:RPPB2257
Size:10µg
Species:Human
Target:RPL12
Synonyms:Ribosomal Protein L12, L12, 60S ribosomal protein L12.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RPL12protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15MNaCl, 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHHSSGLVPRGSH MGSMPPKFDPNEIKVVYLRC TGGEVGATSA LAPKIGPLGL SPKKVGDDIA KATGDWKGLR ITVKLTIQNR QAQIEVVPSASALIIKALKE PPRDRKKQKN IKHSGNITFD EIVNIARQMR HRSLARELSG TIKEILGTAQ SVGCNVDGRHPHDIIDDINS GAVECPAS

Ribosomes, the organelles which catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are comprised of four RNA species and approximately 80 structurally distinct proteins. Ribosomal Protein L12 (RPL12) protein is a member of the L11P family of ribosomal proteins. RPL12 is a component of the 60S subunit, which is located in the cytoplasm. RPL12 binds directly to the 26S rRNA.

RPL12 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 188 amino acids (1-165 a.a) andhaving a molecular mass of 20.2kDa.RPL12 is fused to a 23amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.

UniProt Protein Function:RPL12: a ribosomal protein of the L11P family. Located in the cytoplasm. Binds directly to the 26S rRNA. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit. Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: 9q34Cellular Component: cytosol; focal adhesion; membraneMolecular Function: protein binding; rRNA binding; structural constituent of ribosomeBiological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; ribosomal large subunit assembly and maintenance; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription
UniProt Protein Details:
NCBI Summary:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P30050
NCBI GenInfo Identifier:266921
NCBI Gene ID:6136
NCBI Accession:P30050.1
UniProt Secondary Accession:P30050,Q5VVV2, Q6PB27
UniProt Related Accession:P30050
Molecular Weight:14,199 Da
NCBI Full Name:60S ribosomal protein L12
NCBI Synonym Full Names:ribosomal protein L12
NCBI Official Symbol:RPL12��
NCBI Official Synonym Symbols:L12��
NCBI Protein Information:60S ribosomal protein L12
UniProt Protein Name:60S ribosomal protein L12
UniProt Synonym Protein Names:
Protein Family:50S ribosomal protein
UniProt Gene Name:RPL12��
UniProt Entry Name:RL12_HUMAN
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