Roundabout homolog 4(ROBO4) contains 2 fibronectin type-III domains; 2 Ig-like C2-type (immunoglobulin-like) domains and belongs to the immunoglobulin superfamily.The protein is a receptor for slit proteins; at least for SLIT2; and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins.
Recombinant Human Roundabout homolog 4 is produced by our Mammalian expression system and the target gene encoding Gln28-Arg467 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
74.6 kDa
AP Mol Mass:
87 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman ROBO4 Recombinant Protein Roundabout homolog 4; also known as magic roundabout and ROBO4 is a member of the immunoglobulin superfamily and ROBO family. ROBO
system_update_altDatasheetMouse ROBO4 Recombinant Protein Roundabout homolog 4, also known as magic roundabout and ROBO4 is a member of the immunoglobulin superfamily and ROBO family. ROBO
Human Robo4 ELISARobo4 (Roundabout Guidance Receptor 4) is expressed on the surface of extracellular exosomes and mediates cell-cell adhesion. Robo4 (Roundabout Guidance Receptor 4) is involved in...