Human RGMA Recombinant Protein (RPES3728)
- SKU:
- RPES3728
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human RGMA Recombinant Protein
RGMa; also known as RGM domain family; member A; belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
| Product Name: | Human RGMA Recombinant Protein (RPES3728) |
| Product Code: | RPES3728 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | Repulsive guidance molecule A,RGM domain family member A,RGM |
| Accession: | NP_064596.2 |
| Sequence: | Met 1-Gly 422 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human RGMA isoform 3 (NP_064596.2) (Met 1-Gly 422); without the C-terminal pro peptide; was fused with a polyhistidine tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 43 kDa |
| AP Mol Mass: | 36 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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