Human RCN3 Recombinant Protein (RPPB4431)
- SKU:
- RPPB4431
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96D15
Description
| Product Name: | Human RCN3 Recombinant Protein |
| Product Code: | RPPB4431 |
| Size: | 20µg |
| Species: | Human |
| Target: | RCN3 |
| Synonyms: | Reticulocalbin-3, EF-hand calcium-binding protein RLP49, RCN3, RLP49. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RCN3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMKPSPD AGPHGQGRVH QAAPLSDAPH DDAHGNFQYD HEAFLGREVA KEFDQLTPEE SQARLGRIVD RMDRAGDGDG WVSLAELRAW IAHTQQRHIR DSVSAAWDTY DTDRDGRVGW EELRNATYGH YAPGEEFHDV EDAETYKKML ARDERRFRVA DQDGDSMATR EELTAFLHPE EFPHMRDIVI AETLEDLDRN KDGYVQVEEY IADLYSAEPG EEEPAWVQTE RQQFRDFRDL NKDGHLDGSE VGHWVLPPAQ DQPLVEANHL LHESDTDKDG RLSKAEILGN WNMFVGSQAT NYGEDLTRHH DEL |
Reticulocalbin 3 (RCN3) belongs to the CREC (cab45/reticulocalbin/ ERC45/calumenin) family. RCN3 contains 5 Arg-Xaa-Xaa-Arg motifs, which function as target sequences of SPCs (subtilisin-like proprotein convertases), which is a family of serine endoproteases that proteolytically activate proproteins. The synthesis of PACE4 is induced by association and coexpression with RCN3.
RCN3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 333 amino acids (21-328 a.a) and having a molecular mass of 37.9kDa.RCN3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RCN3: Belongs to the CREC family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 19q13.33Cellular Component: endoplasmic reticulum lumenMolecular Function: protein binding; calcium ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96D15 |
| NCBI GenInfo Identifier: | 28626510 |
| NCBI Gene ID: | 57333 |
| NCBI Accession: | NP_065701.2 |
| UniProt Secondary Accession: | Q96D15,Q9HBZ8 |
| UniProt Related Accession: | Q96D15 |
| Molecular Weight: | 37,493 Da |
| NCBI Full Name: | reticulocalbin-3 |
| NCBI Synonym Full Names: | reticulocalbin 3, EF-hand calcium binding domain |
| NCBI Official Symbol: | RCN3�� |
| NCBI Official Synonym Symbols: | RLP49�� |
| NCBI Protein Information: | reticulocalbin-3; reticulocabin; EF-hand calcium-binding protein RLP49 |
| UniProt Protein Name: | Reticulocalbin-3 |
| UniProt Synonym Protein Names: | EF-hand calcium-binding protein RLP49 |
| Protein Family: | Reticulocalbin |
| UniProt Gene Name: | RCN3�� |
| UniProt Entry Name: | RCN3_HUMAN |
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