Growth Factors & Cytokines Recombinant Proteins

Human RBP7 Recombinant Protein (RPPB0940)

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SKU:
RPPB0940
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q96R05
Research Area:
Growth Factors & Cytokines

Description

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Product Name:Human RBP7 Recombinant Protein
Product Code:RPPB0940
Size:20µg
Species:Human
Target:RBP7
Synonyms:Retinoid-binding protein 7, Cellular retinoic acid-binding protein 4, CRABP4, CRBP4, Cellular retinoic acid-binding protein IV, CRABP-IV, RBP7, MGC70641.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The RBP7 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 2mM DTT and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MPADLSGTWT LLSSDNFEGY MLALGIDFAT RKIAKLLKPQ KVIEQNGDSF TIHTNSSLRN YFVKFKVGEE FDEDNRGLDN RKCKSLVIWD NDRLTCIQKG EKKNRGWTHW IEGDKLHLEM FCEGQVCKQT FQRA

RBP7 is a member of a superfamily of small cytoplasmic proteins which interact with hydrophobic ligands. RBP7 is a newly identified cellular retinol carrier, which is expressed in the kidney, heart and transverse colon in humans.

RBP7 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 154 amino acids (1-134 a.a.) and having a molecular mass of 17.6kDa. The RBP7 is purified by proprietary chromatographic techniques.

UniProt Protein Function:RBP7: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1p36.22

Molecular Function:protein binding

NCBI Summary:Due to its chemical instability and low solubility in aqueous solution, vitamin A requires cellular retinol-binding proteins (CRBPs), such as RBP7, for stability, internalization, intercellular transfer, homeostasis, and metabolism.[supplied by OMIM, May 2004]
UniProt Code:Q96R05
NCBI GenInfo Identifier:20139582
NCBI Gene ID:116362
NCBI Accession:Q96R05.1
UniProt Secondary Accession:Q96R05,Q5SWJ4, B2R517,
UniProt Related Accession:Q96R05
Molecular Weight:15,536 Da
NCBI Full Name:Retinoid-binding protein 7
NCBI Synonym Full Names:retinol binding protein 7
NCBI Official Symbol:RBP7��
NCBI Official Synonym Symbols:CRBP4; CRBPIV��
NCBI Protein Information:retinoid-binding protein 7
UniProt Protein Name:Retinoid-binding protein 7
UniProt Synonym Protein Names:Cellular retinoic acid-binding protein 4; CRABP4; CRBP4; Cellular retinoic acid-binding protein IV; CRABP-IV
Protein Family:Retinoid-binding protein
UniProt Gene Name:RBP7��
UniProt Entry Name:RET7_HUMAN
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