Growth Factors & Cytokines Recombinant Proteins

Human RANK/TNFRSF11A Recombinant Protein (RPES3631)

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SKU:
RPES3631
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines

Description

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Human RANK/TNFRSF11A Recombinant Protein

Receptor Activator of Nuclear Factor ? B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.

Product Name:Human RANK/TNFRSF11A Recombinant Protein (RPES3631)
Product Code:RPES3631
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:CD265, ODFR, TNFRSF11A, TRANCE R, CD265, CD265 antigen, FEO, ODFROSTS, OFE, OPTB7, PDB2, RANK1, Receptor activator of NF-KB, receptor activator of nuclear factor-kappa B, TRANCER, tumor necrosis factor receptor superfamily member 11A
Accession:Q9Y6Q6
Sequence:Ile30-Pro212
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Receptor Activator of NF-kappa-B is produced by our Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:21.1 kDa
AP Mol Mass:25-30 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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