Human RALY Recombinant Protein (RPPB4394)

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SKU:
RPPB4394
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9UKM9

Description

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Product Name:Human RALY Recombinant Protein
Product Code:RPPB4394
Size:25µg
Species:Human
Target:RALY
Synonyms:RALY Heterogeneous Nuclear Ribonucleoprotein, RNA-BindingProtein (Autoantigenic, HnRNP-Associated With Lethal Yellow), HnRNP AssociatedWith Lethal Yellow Protein Homolog, Heterogeneous Nuclear RibonucleoproteinC-Like 2, HnRNP Core Protein C-Like 2, Autoantigen P542, HNRPCL2, P542, RNABinding Protein, Autoantigenic (HnRNP-Associated With Lethal Yellow Homolog(Mouse)), RNA Binding Protein, Autoantigenic (HnRNP-Associated With LethalYellow Homolog), RNA-Binding Protein (Autoantigenic), RNA-Binding Protein Raly,RNA-binding protein Raly.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RALY protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSLKLQA SNVTNKNDPK SINSRVFIGN LNTALVKKSD VETIFSKYGRVAGCSVHKGY AFVQYSNERH ARAAVLGENG RVLAGQTLDI NMAGEPKPDR PKGLKRAASA IYSGYIFDYDYYRDDFYDRL FDYRGRLSPV PVPRAVPVKR PRVTVPLVRRVKTNVPVKLF ARSTAVTTSS AKIKLKSSEL QAIKTELTQI KSNIDALLSRLEQIAAEQKA NPDGKKKGDG GGAGGGGGGG GSGGGGSGGG GGGGSSRPPA PQENTTSEAG LPQGEARTRDDGDEEGLLTH SEEELEHSQD TDADDGALQ

RALY belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) genefamily. RALY takes part in pre-mRNA splicing and also in embryonic development.Moreover, alternate splicing results in multiple transcript variants have beenfound for RALY.

RALY Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 329 amino acids (1-306 a.a) andhaving a molecular mass of 34.9kDa.RALY is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:RALY: Probable-RNA binding protein. Could be a heterogeneous nuclear ribonucleoprotein (hnRNP). May be involved in pre-mRNA splicing. Belongs to the RRM HNRPC family. RALY subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA splicing; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: nucleus

Molecular Function:protein binding; RNA binding; transcription cofactor activity

Biological Process: nuclear mRNA splicing, via spliceosome

NCBI Summary:This gene encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) gene family. This protein may play a role in pre-mRNA splicing and in embryonic development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
UniProt Code:Q9UKM9
NCBI GenInfo Identifier:25091115
NCBI Gene ID:22913
NCBI Accession:Q9UKM9.1
UniProt Secondary Accession:Q9UKM9,Q14621, Q2M365, Q5QPL8, Q9BQX6, Q9UJE3,
UniProt Related Accession:Q9UKM9
Molecular Weight:32kDa
NCBI Full Name:RNA-binding protein Raly
NCBI Synonym Full Names:RALY heterogeneous nuclear ribonucleoprotein
NCBI Official Symbol:RALY��
NCBI Official Synonym Symbols:P542; HNRPCL2��
NCBI Protein Information:RNA-binding protein Raly
UniProt Protein Name:RNA-binding protein Raly
UniProt Synonym Protein Names:Autoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP core protein C-like 2; hnRNP associated with lethal yellow protein homolog
Protein Family:RNA-binding protein
UniProt Gene Name:RALY��
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