Name: Human Rad51 Recombinant Protein (His tag)
SKU: RPES5601
Availability: OutOfStock

Human Rad51 Recombinant Protein (His tag)

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SKU:

RPES5601

Product Type:

Recombinant Protein

Species:

Human

Description

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Mol Mass:	37.07 kDa
AP Mol Mass:	38 kDa
Tag:	N-His
Purity:	> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:	Please contact us for more information.
Bio Activity:	Testing in progress

Sequence:	Ala 2-Asp 339
Accession:	Q06609
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.