Description
| Product Name: | Human RABL5 Recombinant Protein |
| Product Code: | RPPB4376 |
| Size: | 10µg |
| Species: | Human |
| Target: | RABL5 |
| Synonyms: | Rab-like protein 5 isoform a, Rab-like protein 5, RABL5, RAB, Member RAS Oncogene Family-Like 5. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RABL5 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLKAKIL FVGPCESGKT VLANFLTESS DITEYSPTQG VRILEFENPH VTSNNKGTGC EFELWDCGGD AKFESCWPAL MKDAHGVVIV FNADIPSHRK EMEMWYSCFV QQPSLQDTQC MLIAHHKPGS GDDKGSLSLS PPLNKLKLVH SNLEDDPEEI RMEFIKYLKS IINSMSESRD REEMSIMT |
RAB, Member RAS Oncogene Family-Like 5 (RABL5) belongs to the Ras superfamily of small GTP-binding proteins. The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Rab proteins have an essential role in endocytosis or in biosynthetic protein transport. The transporting process of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles includes the movement of carrier vesicles and requires Rab protein function.
RABL5 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (1-185) and having a molecular mass of 23.2 kDa. RABL5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RABL5: Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein; G protein, monomeric; G protein, monomeric, RabChromosomal Location of Human Ortholog: 7q22.1Cellular Component: centrosomeMolecular Function: GTP bindingBiological Process: organelle organization and biogenesis; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H7X7 |
| NCBI GenInfo Identifier: | 195546889 |
| NCBI Gene ID: | 64792 |
| NCBI Accession: | NP_001124292.1 |
| UniProt Secondary Accession: | Q9H7X7,Q49AG1, Q69YV5, Q9BSW4 |
| UniProt Related Accession: | Q9H7X7 |
| Molecular Weight: | 12,393 Da |
| NCBI Full Name: | intraflagellar transport protein 22 homolog isoform b |
| NCBI Synonym Full Names: | intraflagellar transport 22 |
| NCBI Official Symbol: | IFT22�� |
| NCBI Official Synonym Symbols: | RABL5�� |
| NCBI Protein Information: | intraflagellar transport protein 22 homolog |
| UniProt Protein Name: | Intraflagellar transport protein 22 homolog |
| UniProt Synonym Protein Names: | Rab-like protein 5 |
| Protein Family: | Intraflagellar transport protein |
| UniProt Gene Name: | IFT22�� |
| UniProt Entry Name: | IFT22_HUMAN |
