Human RABIF Recombinant Protein (RPPB4375)
- SKU:
- RPPB4375
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P47224
Description
| Product Name: | Human RABIF Recombinant Protein |
| Product Code: | RPPB4375 |
| Size: | 10µg |
| Species: | Human |
| Target: | RABIF |
| Synonyms: | MSS4, RASGFR3, RASGRF3, Rab-interacting factor. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear colorless solution. |
| Formulation: | The RABIF protein solution (0.5mg/ml) contains 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MEPAEQPSELVSAEGRNRKA VLCQRCGSRV LQPGTALFSR RQLFLPSMRK KPALSDGSNP DGDLLQEHWL VEDMFIFENV GFTKDVGNIK FLVCADCEIG PIGWHCLDDK NSFYVALERV SHE |
RABIF is a guanine-nucleotide-releasing protein is involved in vesicular transport. RABIF stimulates GTP-GDP exchange in Sec4 and Rab and binds to a subset of genetically related Rab proteins.
RABIF Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids (1-123 a.a) and having a molecular mass of 16kDa. RABIF is fused to a 20 amino acid His Tag at N-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RasGRF3: Guanine-nucleotide-releasing protein that acts on members of the SCE4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport. Belongs to the DSS4/MSS4 family. |
| UniProt Protein Details: | Protein type:GAPs; GAPs, Rab Chromosomal Location of Human Ortholog: 1q32.1 Molecular Function:protein binding; zinc ion binding; guanyl-nucleotide exchange factor activity Biological Process: protein transport; small GTPase mediated signal transduction; positive regulation of GTPase activity |
| NCBI Summary: | This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and may play a general role in vesicular transport. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P47224 |
| NCBI GenInfo Identifier: | 19923149 |
| NCBI Gene ID: | 5877 |
| NCBI Accession: | NP_002862.2 |
| UniProt Related Accession: | P47224 |
| Molecular Weight: | |
| NCBI Full Name: | guanine nucleotide exchange factor MSS4 |
| NCBI Synonym Full Names: | RAB interacting factor |
| NCBI Official Symbol: | RABIF�� |
| NCBI Official Synonym Symbols: | MSS4; RASGFR3; RASGRF3�� |
| NCBI Protein Information: | guanine nucleotide exchange factor MSS4 |
| UniProt Protein Name: | Guanine nucleotide exchange factor MSS4 |
| UniProt Synonym Protein Names: | Rab-interacting factor |
| Protein Family: | Probable phosphatidylinositol 4-phosphate 5-kinase |
| UniProt Gene Name: | RABIF�� |
| UniProt Entry Name: | MSS4_HUMAN |
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