Human RAB6B Recombinant Protein (RPPB4372)
- SKU:
- RPPB4372
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NRW1
Description
| Product Name: | Human RAB6B Recombinant Protein |
| Product Code: | RPPB4372 |
| Size: | 20µg |
| Species: | Human |
| Target: | RAB6B |
| Synonyms: | Ras-related protein Rab-6B, RAB6B. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RAB6B solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC |
Ras-related protein Rab-6B (RAB6B) is a member of the Rab6 family of the small GTPase superfamily. The Rab6 subfamily consists of 3 different isoforms: Rab6A, Rab6A' and Rab6B. Both Rab6A and Rab6A' are ubiquitously expressed while Rab6B is mainly expressed in brain. Rab6 is a main regulator in the retrograde transfer from endosomes via the Golgi to the ER and may act in retrograde tansport in neuronal cells.
RAB6B Human Recombinant fused with a�20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�228 amino acids (1-208 a.a.) and having a molecular mass of 25.6kDa. The RAB6B is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RAB6B: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric, Rab; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: 3q22.1Cellular Component: Golgi apparatusMolecular Function: myosin V binding; protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NRW1 |
| NCBI GenInfo Identifier: | 13633595 |
| NCBI Gene ID: | 51560 |
| NCBI Accession: | Q9NRW1.1 |
| UniProt Secondary Accession: | Q9NRW1,Q92929, B2R5Z9, B7Z337, D3DND3 |
| UniProt Related Accession: | Q9NRW1 |
| Molecular Weight: | 22,334 Da |
| NCBI Full Name: | Ras-related protein Rab-6B |
| NCBI Synonym Full Names: | RAB6B, member RAS oncogene family |
| NCBI Official Symbol: | RAB6B�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ras-related protein Rab-6B |
| UniProt Protein Name: | Ras-related protein Rab-6B |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB6B�� |
| UniProt Entry Name: | RAB6B_HUMAN |
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