Human RAB6B Recombinant Protein (RPPB4372)

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SKU:
RPPB4372
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9NRW1

Description

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Product Name:Human RAB6B Recombinant Protein
Product Code:RPPB4372
Size:20µg
Species:Human
Target:RAB6B
Synonyms:Ras-related protein Rab-6B, RAB6B.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The RAB6B solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC

Ras-related protein Rab-6B (RAB6B) is a member of the Rab6 family of the small GTPase superfamily. The Rab6 subfamily consists of 3 different isoforms: Rab6A, Rab6A' and Rab6B. Both Rab6A and Rab6A' are ubiquitously expressed while Rab6B is mainly expressed in brain. Rab6 is a main regulator in the retrograde transfer from endosomes via the Golgi to the ER and may act in retrograde tansport in neuronal cells.

RAB6B Human Recombinant fused with a�20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�228 amino acids (1-208 a.a.) and having a molecular mass of 25.6kDa. The RAB6B is purified by proprietary chromatographic techniques.

UniProt Protein Function:RAB6B: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric, Rab; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: 3q22.1Cellular Component: Golgi apparatusMolecular Function: myosin V binding; protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9NRW1
NCBI GenInfo Identifier:13633595
NCBI Gene ID:51560
NCBI Accession:Q9NRW1.1
UniProt Secondary Accession:Q9NRW1,Q92929, B2R5Z9, B7Z337, D3DND3
UniProt Related Accession:Q9NRW1
Molecular Weight:22,334 Da
NCBI Full Name:Ras-related protein Rab-6B
NCBI Synonym Full Names:RAB6B, member RAS oncogene family
NCBI Official Symbol:RAB6B��
NCBI Official Synonym Symbols:
NCBI Protein Information:ras-related protein Rab-6B
UniProt Protein Name:Ras-related protein Rab-6B
UniProt Synonym Protein Names:
Protein Family:Ras-related protein
UniProt Gene Name:RAB6B��
UniProt Entry Name:RAB6B_HUMAN
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