Human RAB5C Recombinant Protein (RPPB4370)
- SKU:
- RPPB4370
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P51148
Description
| Product Name: | Human RAB5C Recombinant Protein |
| Product Code: | RPPB4370 |
| Size: | 20µg |
| Species: | Human |
| Target: | RAB5C |
| Synonyms: | L1880, RAB5CL, RAB5L, RABL, Ras-related protein Rab-5C, RAB5C. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RAB5C solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAGRGGA ARPNGPAAGN KICQFKLVLL GESAVGKSSL VLRFVKGQFH EYQESTIGAA FLTQTVCLDD TTVKFEIWDT AGQERYHSLA PMYYRGAQAA IVVYDITNTD TFARAKNWVK ELQRQASPNI VIALAGNKAD LASKRAVEFQ EAQAYADDNS LLFMETSAKT AMNVNEIFMA IAKKLPKNEP QNATGAPGRN RGVDLQENNP ASRSQCCSN |
RAB5C is a part of the Ras-related protein family. Members of the Rab protein family are small GTPases of the Ras superfamily guarantee reliability in the process of docking and fusion of vesicles with their right acceptor compartment.
RAB5C Human Recombinant produced in E. coli is a single polypeptide chain containing 239 amino acids (1-216) and having a molecular mass of 25.9kDa. RAB5C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; G protein, monomeric; G protein; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: early endosome; endocytic vesicle; intracellular membrane-bound organelle; lipid particle; lysosomal membrane; plasma membrane Molecular Function:GDP binding; GTPase activity; protein binding Biological Process: plasma membrane to endosome transport; regulation of endocytosis |
| NCBI Summary: | Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | P51148 |
| NCBI GenInfo Identifier: | 38258923 |
| NCBI Gene ID: | 5878 |
| NCBI Accession: | P51148.2 |
| UniProt Secondary Accession: | P51148,Q6FH55, Q9P0Y5, F8W1H5, |
| UniProt Related Accession: | P51148 |
| Molecular Weight: | 27,036 Da |
| NCBI Full Name: | Ras-related protein Rab-5C |
| NCBI Synonym Full Names: | RAB5C, member RAS oncogene family |
| NCBI Official Symbol: | RAB5C�� |
| NCBI Official Synonym Symbols: | RABL; L1880; RAB5L; RAB5CL�� |
| NCBI Protein Information: | ras-related protein Rab-5C |
| UniProt Protein Name: | Ras-related protein Rab-5C |
| UniProt Synonym Protein Names: | L1880; RAB5L |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB5C�� |
| UniProt Entry Name: | RAB5C_HUMAN |
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