Human RAB2B Recombinant Protein (RPPB4358)
- SKU:
- RPPB4358
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WUD1
Description
| Product Name: | Human RAB2B Recombinant Protein |
| Product Code: | RPPB4358 |
| Size: | 20µg |
| Species: | Human |
| Target: | RAB2B |
| Synonyms: | Ras-related protein Rab-2B, RAB2B. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RAB2B protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1mM DTT and 0.15M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMTYAYL FKYIIIGDTG VGKSCLLLQF TDKRFQPVHD LTIGVEFGAR MVNIDGKQIK LQIWDTAGQE SFRSITRSYY RGAAGALLVY DITRRETFNH LTSWLEDARQ HSSSNMVIML IGNKSDLESR RDVKREEGEA FAREHGLIFM ETSAKTACNV EEAFINTAKE IYRKIQQGLF DVHNEANGIK IGPQQSISTS VGPSASQRNS RDIGSNSGCC |
Rab2B is a member of the small GTPase superfamily, whose members are nontransforming monomeric GTP-binding proteins of the Ras superfamily and contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins engaged in vesicular fusion and trafficking.
RAB2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 240 amino acids (1-216 a.a.) and having a molecular mass of 26.8kDa. RAB2B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RAB2B: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential). Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric; G protein; G protein, monomeric, RabChromosomal Location of Human Ortholog: 14q11.2Molecular Function: protein bindingBiological Process: positive regulation of exocytosis |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006] |
| UniProt Code: | Q8WUD1 |
| NCBI GenInfo Identifier: | 28436385 |
| NCBI Gene ID: | 84932 |
| NCBI Accession: | Q8WUD1.1 |
| UniProt Secondary Accession: | Q8WUD1,Q6NZ33, B2RD03, D3DS24 |
| UniProt Related Accession: | Q8WUD1 |
| Molecular Weight: | 16,667 Da |
| NCBI Full Name: | Ras-related protein Rab-2B |
| NCBI Synonym Full Names: | RAB2B, member RAS oncogene family |
| NCBI Official Symbol: | RAB2B�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ras-related protein Rab-2B |
| UniProt Protein Name: | Ras-related protein Rab-2B |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB2B�� |
| UniProt Entry Name: | RAB2B_HUMAN |
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