Human RAB24 Recombinant Protein (RPPB4354)

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RPPB4354

Description

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Product Name:Human RAB24 Recombinant Protein
Product Code:RPPB4354
Size:20µg
Species:Human
Target:RAB24
Synonyms:RAB24 member RAS oncogene family, ras-related protein Rab-24.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The RAB24 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl, 0.1M EDTA and 30% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH

RAB24 is a member of the small GTPase superfamily which regulates intracellular protein transferring, nonetheless the specific role of RAB24 has not yet been revealed. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures which suggests connection to autophagy-related courses. RAB24 demonstrates uncommon characteristics such as low intrinsic GTPase activity, and is incompetently prenylated when compared with other Rab proteins indicates that RAB24 has a distinctive part in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope.

RAB24 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-203) and having a molecular mass of 25.7 kDa.RAB24 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:May be involved in autophagy-related processes.
NCBI Summary:RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]
UniProt Code:Q969Q5
NCBI GenInfo Identifier:72534833
NCBI Gene ID:53917
NCBI Accession:NP_001026847.1
UniProt Secondary Accession:Q969Q5,Q7Z4Z7,
UniProt Related Accession:Q969Q5
Molecular Weight:23,124 Da
NCBI Full Name:ras-related protein Rab-24
NCBI Synonym Full Names:RAB24, member RAS oncogene family
NCBI Official Symbol:RAB24��
NCBI Protein Information:ras-related protein Rab-24
UniProt Protein Name:Ras-related protein Rab-24
Protein Family:Ras-related protein
UniProt Gene Name:RAB24��
UniProt Entry Name:RAB24_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q969Q5
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