Human RAB1B Recombinant Protein (RPPB4350)

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SKU:
RPPB4350
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9H0U4

Description

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Product Name:Human RAB1B Recombinant Protein
Product Code:RPPB4350
Size:10µg
Species:Human
Target:RAB1B
Synonyms:Ras-related protein Rab-1B, RAB1B.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The RAB1B solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) and 10% Glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MNPEYDYLFK LLLIGDSGVG KSCLLLRFAD DTYTESYIST IGVDFKIRTI ELDGKTIKLQ IWDTAGQERF RTITSSYYRG AHGIIVVYDV TDQESYANVK QWLQEIDRYA SENVNKLLVG NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KRMGPGAASG GERPNLKIDS TPVKPAGGGC C

RAB1B belongs to the RAB protein family, these proteins are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane bound organelles. RAB1B protein functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi.

RAB1B Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 221 amino acids (1-201 a.a.) and having a molecular mass of 24.3kDa. The RAB1B is purified by proprietary chromatographic techniques.

UniProt Protein Function:RAB1B: Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Belongs to the small GTPase superfamily. Rab family.
UniProt Protein Details:

Protein type:G protein, monomeric; G protein, monomeric, Rab; G protein

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; mitochondrion; pre-autophagosomal structure membrane; ER-Golgi intermediate compartment

Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; ER to Golgi vesicle-mediated transport; autophagy; virus assembly; Rab protein signal transduction

NCBI Summary:Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]
UniProt Code:Q9H0U4
NCBI GenInfo Identifier:23396834
NCBI Gene ID:81876
NCBI Accession:Q9H0U4.1
UniProt Secondary Accession:Q9H0U4,A8K7S1,
UniProt Related Accession:Q9H0U4
Molecular Weight:201
NCBI Full Name:Ras-related protein Rab-1B
NCBI Synonym Full Names:RAB1B, member RAS oncogene family
NCBI Official Symbol:RAB1B��
NCBI Protein Information:ras-related protein Rab-1B; small GTP-binding protein
UniProt Protein Name:Ras-related protein Rab-1B
Protein Family:Ras-related protein
UniProt Gene Name:RAB1B��
UniProt Entry Name:RAB1B_HUMAN
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