Human R-spondin-1 / RSPO1 ELISA Kit

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SKU:
HUFI01922
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q2MKA7
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich
Synonyms:
Cristin 3, RSPO1, CRISTIN3, FLJ40906Roof plate-specific spondin-1, hRspo1, roof plate-specific spondin, RSPO, RSPONDIN, R-spondin homolog, Xenopus laevis, R-spondin1, R-spondin-1
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human R-spondin-1 / RSPO1 ELISA

R-spondin-1 / RSPO1 encodes a secreted activator protein with cysteine-rich furin-like domains and a thrombospondin type 1 domain. R-spondin-1 / RSPO1 is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. R-spondin-1 / RSPO1 induces cell proliferation and increases intestinal epithelial healing. Diseases associated with R-spondin-1 / RSPO1 include Palmoplantar Hyperkeratosis With Squamous Cell Carcinoma Of Skin, and Hermaphroditism.

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