Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors.
Product Name:
Human PTPN6/SH-PTP1 Recombinant Protein (RPES3403)
Recombinant Human Protein-Tyrosine Phosphatase 1C is produced by our E.coli expression system and the target gene encoding Lys243-Ile541 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
35.4 kDa
AP Mol Mass:
33 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 25mM TrisHCl, 2mM ?-ME, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
system_update_altDatasheetMouse PTPN6/SH-PTP1 Recombinant Protein PTPN6 is an enzyme which belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a v
system_update_altDatasheetHuman PTP1B/PTPN1 Recombinant Protein PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate