Human PTGER4 Full-Length Bioactive Membrane Protein (HDFP078)

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SKU:
HDFP078
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P35408

Description

system_update_altDatasheet
Product nameHuman PTGER4 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP078
Product CategoryFull Length Transmembrane Proteins
Target:PTGER4
Uniprot:P35408
Description:Human PTGER4 full length protein-synthetic nanodisc
Molecular Weight:The human full length PTGER4 protein has a MW of 53.1 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:EP4; EP4R
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Delivery:3-4 weeks
UsageResearch use only
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