Human PTGDR2 Full-Length Bioactive Membrane Protein (HDFP106)

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SKU:
HDFP106
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9Y5Y4

Description

system_update_altDatasheet
Product nameHuman PTGDR2 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP106
Product CategoryFull Length Transmembrane Proteins
Target:PTGDR2
Uniprot:Q9Y5Y4
Description:Human PTGDR2 full length protein-synthetic nanodisc
Molecular Weight:The human full length PTGDR2 protein has a MW of 43.7 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CD294; CRTH2; DL1R; DP2; GPR44
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
Delivery:3-4 weeks
UsageResearch use only
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