Human PSG1 Recombinant Protein (RPPB4318)
- SKU:
- RPPB4318
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P11464
Description
| Product Name: | Human PSG1 Recombinant Protein |
| Product Code: | RPPB4318 |
| Size: | 20µg |
| Species: | Human |
| Target: | PSG1 |
| Synonyms: | Pregnancy Specific Beta-1-Glycoprotein 1, PSBG1, B1G1, Fetal Liver Non-Specific Cross-Reactive Antigen 1/2, Pregnancy-Specific Beta-1 Glycoprotein C/D, CD66 Antigen-Like Family Member F, PS-Beta-C/D, PS-Beta-G-1, FL-NCA-1/2, PSBG-1, PSGGA, PSG95, SP1, Pregnancy-Specific Beta-1-Glycoprotein 1, Pregnancy-Specific B-1 Glycoprotein, Pregnancy-Specific Glycoprotein 1, CD66f Antigen, DHFRP2, PSGIIA, CD66f, PBG1, PSG1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The PSG1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSQVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP |
Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) is a member of a subgroup of transcription factors which are phosphorylated upon binding to promoter sequences. PSGs belong to the carcinoembryonic antigen (CEA) family and function as early biochemical markers of syncytiotrophoblast formation. Furthermore, PSG1 is assumed to mediate placental vascular morphogenesis by enhancing VEGF-A production and endothelial tube formation. PSG1 is a major product of the syncytiotrophoblast, reaching concentrations of 100- 290 mg/l at term in the serum of pregnant women.
PSG1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 408 amino acids (35-419) and having a molecular mass of 45.9 kDa.PSG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| NCBI Summary: | The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009] |
| UniProt Code: | P11464 |
| NCBI GenInfo Identifier: | 129661 |
| NCBI Gene ID: | 5669 |
| NCBI Accession: | P11464.1 |
| UniProt Secondary Accession: | P11464,O75236, P11462, P11463, Q15231, Q15241, Q15243 Q16660, Q6ICR4, Q9P1W5, Q9UQ79, |
| UniProt Related Accession: | P11464 |
| Molecular Weight: | 47,866 Da |
| NCBI Full Name: | Pregnancy-specific beta-1-glycoprotein 1 |
| NCBI Synonym Full Names: | pregnancy specific beta-1-glycoprotein 1 |
| NCBI Official Symbol: | PSG1�� |
| NCBI Official Synonym Symbols: | SP1; B1G1; PBG1; CD66f; PSBG1; PSG95; PSGGA; DHFRP2; PSBG-1; PSGIIA; FL-NCA-1/2; PS-beta-C/D; PS-beta-G-1�� |
| NCBI Protein Information: | pregnancy-specific beta-1-glycoprotein 1 |
| UniProt Protein Name: | Pregnancy-specific beta-1-glycoprotein 1 |
| UniProt Synonym Protein Names: | CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD_antigen: CD66f |
| Protein Family: | Pregnancy-specific beta-1-glycoprotein |
| UniProt Gene Name: | PSG1�� |
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