Human PRPSAP2 Recombinant Protein (RPPB4479)

(No reviews yet) Write a Review
SKU:
RPPB4479
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O60256

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human PRPSAP2 Recombinant Protein
Product Code:RPPB4479
Size:20µg
Species:Human
Target:PRPSAP2
Synonyms:PAP41, Phosphoribosyl pyrophosphate synthase-associated protein 2, PRPP synthase-associated protein 2, 41 kDa phosphoribosypyrophosphate synthetase-associated protein, PRPSAP2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The PRPSAP2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMFCVTPP ELETKMNITK GGLVLFSANS NSSCMELSKK IAERLGVEMG KVQVYQEPNR ETRVQIQESV RGKDVFIIQT VSKDVNTTIM ELLIMVYACK TSCAKSIIGV IPYFPYSKQC KMRKRGSIVS KLLASMMCKA GLTHLITMDL HQKEIQGFFN IPVDNLRASP FLLQYIQEEI PDYRNAVIVA KSPASAKRAQ SFAERLRLGI AVIHGEAQDA ESDLVDGRHS PPMVRSVAAI HPSLEIPMLI PKEKPPITVV GDVGGRIAII VDDIIDDVDS FLAAAETLKE RGAYKIFVMA THGLLSSDAP RRIEESAIDE VVVTNTIPHE VQKLQCPKIK TVDISMILSE AIRRIHNGES MSYLFRNIGL DD

Phosphoribosyl Pyrophosphate Synthetase-Associated Protein 2 (PRPSAP2) is a protein which relates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine, pyrimidine, histidine, tryptophan and NAD. PRS is a complex with 2 catalytic subunits and 2 associated subunits. PRPSAP2 encodes a non-catalytic associated subunit of PRS.

PRPSAP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 392 amino acids (1-369) and having a molecular mass of 43.3kDa. PRPSAP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
NCBI Summary:This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
UniProt Code:O60256
NCBI GenInfo Identifier:4506133
NCBI Gene ID:5636
NCBI Accession:NP_002758
UniProt Related Accession:O60256
Molecular Weight:31kDa; 35kDa; 36kDa; 40kDa
NCBI Full Name:phosphoribosyl pyrophosphate synthase-associated protein 2 isoform 1
NCBI Synonym Full Names:phosphoribosyl pyrophosphate synthetase associated protein 2
NCBI Official Symbol:PRPSAP2��
NCBI Official Synonym Symbols:PAP41��
NCBI Protein Information:phosphoribosyl pyrophosphate synthase-associated protein 2
UniProt Protein Name:Phosphoribosyl pyrophosphate synthase-associated protein 2
UniProt Synonym Protein Names:41 kDa phosphoribosypyrophosphate synthetase-associated protein; PAP41
Protein Family:Phosphoribosyl pyrophosphate synthase-associated protein
UniProt Gene Name:PRPSAP2��
View AllClose

0 Reviews

View AllClose

Related Products