Human Proteinase-3 / PRTN3 ELISA Kit

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SKU:
HUFI00332
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P24158
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
PR3, Proteinase 3, ACPA, AGP7, C-ANCA, MBN, MBT, Myeloblastin, NP4, PRTN3, ACPA, AGP7PR3, azurophil granule protein 7, C-ANCA, Leukocyte proteinase 3, MBN, MBT, myeloblastin, Neutrophil proteinase 4, NP4, NP-4, P29C-ANCA antigen, PR-3CANCA
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Proteinase-3 / PRTN3 ELISA

Proteinase-3 / PRTN3 is a member of the proteinase-activated receptor family that is activated by serine proteases. Proteinase-3 / PRTN3 is expressed in many cell types including endothelial cells, platelets and immune cells. The activation of Proteinase-3 / PRTN3 by trypsin promotes the release of TNF-alpha, interleukin-12, and granulocyte/macrophage colony stimulating factor. Proteinase-3 / PRTN3 associated diseases include granulomatosis with polyangiitis, and renal disease.

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