Cardiovascular Recombinant Proteins

Human PROS1/Protein S Recombinant Protein (RPES0217)

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SKU:
RPES0217
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cardiovascular

Description

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Human PROS1/Protein S Recombinant Protein

PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

Product Name:Human PROS1/Protein S Recombinant Protein (RPES0217)
Product Code:RPES0217
Size:100µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:PROS,Protein S,PS21,PS22,PS23,PS24,PS25,PSA,THPH5,THPH6
Accession:P07225
Sequence:Met 1-Ser676
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:74.1 kDa
AP Mol Mass:69-89 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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