Human PROKR1 Full-Length Bioactive Membrane Protein (HDFP083)

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SKU:
HDFP083
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q8TCW9

Description

system_update_altDatasheet
Product nameHuman PROKR1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP083
Product CategoryFull Length Transmembrane Proteins
Target:PROKR1
Uniprot:Q8TCW9
Description:Human PROKR1 full length protein-synthetic nanodisc
Molecular Weight:The human full length PROKR1 protein has a MW of 44.6 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:GPR73; GPR73a; PK-R1; PKR1; ZAQ
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
Delivery:3-4 weeks
UsageResearch use only
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