Human Proenkephalin-B / PDYN ELISA Kit

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SKU:
HUFI00887
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P01213
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Competitive
Synonyms:
PDYN, Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Proenkephalin-B / PDYN ELISA Kit

Proenkephalin-B/PDYN is a proprotein that is proteolytically processed to generate the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin.The kappa-opioid receptors are triggered by these peptides, which bind to them. Dynorphin is involved in mood regulation after administration of various psychoactive chemicals, including cocaine. One of the most common diseases linked to PDYN is Spinocerebellar Ataxia 23, which causes loss of motor control. Cocaine Dependence and other neurodegenerative disease are also associated with it. Signaling by GPCR and Peptide ligand-binding receptors are among its connected pathways.

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