Human PRCP Recombinant Protein (RPES3934)

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SKU:
RPES3934
Product Type:
Recombinant Protein
Species:
Human

Description

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Human PRCP Recombinant Protein

Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.

Product Name:Human PRCP Recombinant Protein (RPES3934)
Product Code:RPES3934
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP
Accession:P42785
Sequence:Leu22-His496
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:54.5 kDa
AP Mol Mass:72 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM NaAc-HAc,150mM NaCl,10%Glycerol,pH4.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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