Human PPM1G/PP2C-gamma Recombinant Protein (RPES2411)
- SKU:
- RPES2411
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human PPM1G/PP2C-gamma Recombinant Protein
Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.
| Product Name: | Human PPM1G/PP2C-gamma Recombinant Protein (RPES2411) |
| Product Code: | RPES2411 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Protein Phosphatase 1G, Protein Phosphatase 1C, Protein Phosphatase 2C Isoform Gamma, PP2C-Gamma, Protein Phosphatase Magnesium-Dependent 1 Gamma, PPM1G, PP2CG,PP2CGAMMA |
| Accession: | O15355 |
| Sequence: | Met 317-Asp 546 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human PPM1G (O15355) C-terminal fragment (Met 317-Asp 546) was expressed; with a polyhistidine tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.6 kDa |
| AP Mol Mass: | 30 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris; 1mM DTT; 20% glycerol; pH 7.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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