Human PPARgC1A / Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ELISA Kit

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SKU:
HUFI01061
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9UBK2
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
PPARGC1A, Peroxisome prolifeRator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6, LEM6, PGC1, PGC1A, PPARGC1, PGC-1v,
Reactivity:
Human
Research Area:
Cell Biology

Description

Human PPARgC1A / Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ELISA Kit

PPARgC1A is a transcriptional coactivator that controls the expression of genes involved in energy metabolism. PPARgC1A interacts with PPARgamma, allowing it to interact with a variety of transcription factors. PPARgC1A can interact with cAMP response element binding protein (CREB) and nuclear respiratory factors, regulating their activities (NRFs). PPARgC1A is a major regulator of muscle fibre type determination and provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis. PPARgC1A may also play a role in the regulation of cellular cholesterol homoeostasis, as well as the development of obesity.

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