DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).
Product Name:
Human POLD2 Recombinant Protein (RPES2482)
Product Code:
RPES2482
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
DNA Polymerase Delta Subunit 2, DNA Polymerase Delta Subunit p50, POLD2
Accession:
P49005
Sequence:
Met 1-Pro469
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human DNA Polymerase Delta Subunit 2 is produced by our E.coli expression system and the target gene encoding Met1-Pro469 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
52.3 kDa
AP Mol Mass:
56 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of PBS, 10% Glycerol, pH 7.4.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.